Mimics of Optic Neuritis in Neuromyelitis Optica Spectrum Disorder: A Case Report

ABSTRACT

The optic nerve can be involved in a myriad of pathologies underscoring the importance of ruling out both surgical as well as medical causes. Often, it is the temporal profile, clinical presentation and imaging that helps to establish the final diagnosis. Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder involving the optic nerves and the spinal cord, which if promptly and adequately managed, may yield gratifying outcomes. We report an unusual presentation of NMOSD, mimicking a compressive optic neuropathy. A comprehensive review of the history, extensive investigations including brain and spinal cord imaging, and positive anti-aquaporin 4 antibodies helped in the definitive management.

KEYWORDS:

• Neuromyelitis optica
• optic nerve
• tuberculum sellae meningioma
• radiation-induced optic neuropathy

Author contribution

Nandita Prabhat: Acquisition of data, analysis and interpretation of data; manuscript preparation.

Karthik Vinay Mahesh: Involved in diagnosing the patient and manuscript revision.

Aastha Takkar: Drafting the article and revising it critically for important intellectual content.

Manjul Tripathi: Revising the article for important intellectual content.

Chirag Ahuja: Manuscript revision and correction.

Ramandeep Singh: Manuscript revision and correction.