Quantitative Optical Coherence Tomography Angiography in Patients with Moyamoya Vasculopathy: A Pilot Study

ABSTRACT

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. We sought to investigate and quantify retinal vascular changes in patients with MM vasculopathy (MMV) using optical coherence tomography angiography (OCTA) compared to healthy controls. Our findings reveal retinal microvascular changes in patients with MMV and highlights the potential of OCTA imaging for the detection of subclinical retinal pathology.

KEYWORDS:

• Neuro-ophthalmology
• optical coherence tomography angiography
• retina
• moyamoya vasculopathy

Declaration of interest statement

None of the authors have any financial interests or conflicts related to this research to disclose.

Ethical considerations

This study adhered to the Declaration of Helsinki and was approved by the Clinical Research Ethics Boards at the University of British Columbia (H18-02488).

Additional information

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.