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The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery
Volume 37, 2018 - Issue 4
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Case Report

Orbital granulomatosis with polyangiitis masquerading as invasive fungal sinusitis

David XuStein Eye Institute, University of California, Los Angeles, CA, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3649-4746View further author information
ORCID Icon,
Shawn R. LinStein Eye Institute, University of California, Los Angeles, CA, USAView further author information
,
Laura BonelliStein Eye Institute, University of California, Los Angeles, CA, USAView further author information
,
Ben J. GlasgowStein Eye Institute, University of California, Los Angeles, CA, USAView further author information
&
Robert A. GoldbergStein Eye Institute, University of California, Los Angeles, CA, USAView further author information
Pages 309-312 | Received 01 Jan 2017, Accepted 29 Dec 2017, Published online: 05 Jan 2018
 
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ABSTRACT

A 55-year-old man presented with unilateral orbital inflammation and no light perception vision. Imaging revealed infiltrative enhancement of the optic nerve, orbit, and intracranial tissue. The case was suspicious for invasive fungal disease, but ultimate workup and orbital biopsy revealed granulomatosis with polyangiitis. The patient’s inflammation resolved with corticosteroid and rituximab therapy. Granulomatosis with polyangiitis is a systemic vasculitis that can mimic a number of orbital pathologies.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Additional information

Notes on contributors

David Xu

DX: acquisition, analysis, interpretation, drafting of manuscript, critical revision, supervision

Shawn R. Lin

SRL: analysis, interpretation, drafting of manuscript, critical revision

Laura Bonelli

LB: analysis, interpretation, drafting of manuscript, critical revision

Ben J. Glasgow

BJG: analysis, interpretation, drafting of manuscript, critical revision

Robert A. Goldberg

RAG: analysis, interpretation, drafting of manuscript, critical revision

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