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Abstract
The author describes a case of pancreatic heterotopia in the gastric antrum detected after histopathological and ultrastructural studies. Bioptic fragments were processed in part for optic microscopy and in part for electron transmission microscopy. Regressive changes were found in the cytoplasm of the exocrine secreting epithelia that led to necrosis of the cells. The changes are consequential and more markedly involve the base area of the secretory epithelia. The changes observed are to be attributed to the absence of excretory activity by the epithelia due to regressive damage of the organelles carrying out this activity.