Ozone: Science & Engineering

The Journal of the International Ozone Association

Volume 39, 2017 - Issue 3

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Original Articles

A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

Francesca SerioDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

http://orcid.org/0000-0002-2782-2798

Graziano PizzolanteDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

Giuseppe CozzolinoDepartment of Vascular and Endovascular Surgery, Hospital “Cardinal G. Panico”, 73039Tricase, Italy

Maria D’AlbaDepartment of Nephrology and Dialysis, Hospital “V. Delli Ponti”, 73020Scorrano, Italy

Francesco BagordoDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

http://orcid.org/0000-0001-5208-5382

Mattia De GiorgiDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

Tiziana GrassiDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

http://orcid.org/0000-0003-1200-2778

Adele IdoloDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

Marcello GuidoDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, Italy

Antonella De DonnoDepartment of Biological and Environmental Science and Technology, University of the Salento, 73100Lecce, ItalyCorrespondence[email protected]

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ABSTRACT

The objective of this study was to investigate the potential in vitro biological properties of Oz.Or.Oil 30, a new formulation composed of 30% ozonated sunflower seed oil, which is believed to keep skin smooth and moisturized, supporting repair processes, tissue regeneration and re-epithelialization of wounds. The antibacterial activity, the qualitative and quantitative evaluation of the cytotoxic effect of the formulation on cultures of Vero cells and 3T3 fibroblasts showed that Oz.Or.Oil 30 merits further in vivo study using clinical-laboratory correlations, because it could be suggested as an alternative therapy against bacterial and fungal diseases.

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A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

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A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

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