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Ozone: Science & Engineering
The Journal of the International Ozone Association
Volume 43, 2021 - Issue 1
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Review

Critical Review and Research Needs of Ozone Applications Related to Virus Inactivation: Potential Implications for SARS-CoV-2

ORCID Icon, ORCID Icon, , ORCID Icon, ORCID Icon, , , & ORCID Icon show all
Pages 2-20 | Received 06 Oct 2020, Accepted 16 Oct 2020, Published online: 21 Dec 2020
 

ABSTRACT

Ozone disinfection has demonstrated high efficacy against enveloped and non-enveloped viruses, including viruses similar in morphology to SARS-CoV-2. Due to this efficacy, numerous gaseous and aqueous phase ozone applications have emerged to potentially inhibit virus persistence in aerosols, surfaces, and water. This review identifies the exposure requirements for virus inactivation and important safety considerations for applications within the built environment (i.e. occupied/unoccupied spaces, air/water/wastewater treatment) and healthcare settings (i.e. ozone therapy, dentistry, handwashing, treatment of personal protection equipment (PPE)). Current research needs are presented to advance the utilization of ozone as a mitigation strategy.

Disclaimer

Statements regarding clinical trials and procedures do not imply subsequent acceptance by FDA, EPA, NIH, CDC, ADA or other international government regulatory agencies.

Supplementary material

Supplemental data for this article can be accessed on the publisher’s website

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