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Original Articles

Aggregation Behavior of Nonionic Clycolipid Vesicles in Acidic Region

, , , &
Pages 907-913 | Received 01 Oct 1999, Accepted 03 Apr 2000, Published online: 27 Apr 2007
 

Abstract

Large unilamellar vesicles composed of a nonionic synthetic glycotipid, 1,3 - di- 0 - phylanyl -2-0-(β- maltotriosyl ) glycerol show pH-dependent aggregation - dissocialion process, that is, vesicle aggregation occurs in the lower pH region and vesicle dissociation occurs in the higher pH region. This process is almost reversible and the aggregation threshold pH is dependent on NaCl concentration. Fluorescence technique has been applied to study whether the vesicle fusion occurs or not during the aggregation-dissociation process. It is concluded pH can only induce the aggregation of this nonionic glycoltpid vesicle.

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