Hydrolysis of BNPP Catalyzed by the Crowned Schiff Base Co(II) Complex Containing Benzoaza‐15‐Crown‐5 in Micellar Solution

It has been reported that three aza crowned Schiff base cobalt (II) complexes were synthesized and characterized, and the metallomicelle made up of the cobalt (II) complexes and surfactants(Brij35, CTAB, LSS), as mimic hydrolytic metalloenzyme, was used in catalytic hydrolysis of bis(4‐nitrophenyl) phosphate (BNPP). The analysis of specific absorption spectrums of the hydrolytic reaction systems indicated that key intermediates made up of BNPP and Co (II) complexes are formed in the reaction process of BNPP catalytic hydrolysis. The mechanism of BNPP catalytic hydrolysis proposed is based on the analytic result of specific absorption spectra. Based on the mechanism proposed, a kinetic mathematical model for the calculation of the kinetic parameter of BNPP catalytic hydrolysis has been established. The acid effect of reaction system, structure effect of the complexes, effect of temperature and effect of micelles on the rate of BNPP hydrolysis catalyzed by the complexes have been discussed.

Keywords:

• Crowned schiff base cobalt (II) complexes
• metallomicelle
• mimic hydrolase
• catalytic kinetics
• hydrolysis of phosphate diesters

This work was supported by the National Natural Science Foundation of China (Grant No.20173038 and 2005A145) and importance item of the think factory of Zigong (05G2019) and the Education Department of Sichuan Government (No. 2005D007).