Ultra Moisturizing Skin Whitening Lotion Enriched with Tocotrienols

Abstract

A two-in-one product, a skin whitening lotion enriched with tocotrienols that ultra moisturizes and lightens, was successfully prepared. The basic formulation for this product was prepared by constructing a ternary phase diagram consisting of medium chain triglycerides (MCT), mixed glucose-based emulsifiers, and deionized water at 80°C. The right ratio of these compounds was selected based on liquid crystalline region to produce a stable product. Other palm-based materials were added to the basic formulation. The product was found to be stable for more than 3 months upon storage stability test. The mean droplet size is 10 µm with a monomodal distribution pattern which prevents agglomeration. This decreases Brownian motion, thus prolonging its stability. Long-term acute moisturizing tests showed a significant increase of between 21.2% and 15.4% hydration for 5 and 6 weeks, respectively. The efficacy testing on 20 subjects confirmed a reduction in melanin content, lightening the skin in 4 weeks.

Keywords:

• Droplet size
• lamella liquid crystalline structure
• melanin reduction
• palm-based materials
• tocotrienols
• ultra-moisturizing

Acknowledgments

The authors would like to thank the staff of Golden Hope Research Sdn Bhd, for their assistance in the conduction of the trials.