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Abstract
Novel DNA-chitosan particles were prepared based on associative phase separation and interfacial diffusion. These particles formed at water/water emulsion type interfaces were characterized with respect to several properties including stability, DNA conformational state, and entrapment and release of DNA. In particular it was found that the chitosan molecular weight is a good controlling parameter.
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This work was supported by grants from the Fundação para a Ciência e Tecnologia (POCTI/QUI/58689/2004 and PTDC/QUI/67962/2006) and a grant from FEDER through the Program (PTDCOCI 2010).
