Preparation and evaluation of microcapsules containing Rimulus Cinnamon and Angelica Sinenis essential oils

Abstract

Starch sodium octenyl succinate (SSOS) and maltodextrin (MD) are commonly used as wall materials to protect bioactive compounds, such as essential oils volatiles. In this work, Rimulus Cinamon (RC) and Angelica Sinenis (AS) essential oils (EOs) were encapsulated in (SSOS/MD) composite capsules via spray drying. The microcapsules were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and thermogravimetric (TG). The particle size, Zeta potential, drug loading (DL), encapsulation efficiency (EE), stability and in vitro release of the EOs microcapsules were investigated. The average particle size of microcapsules and emulsion was 12.6 ± 1.09 μm and 0.22 ± 0.01 μm, respectively. The DL% and EE% of microcapsules were 16.3 ± 0.40% and 96.6 ± 1.17%. No phase separation was found in the emulsion within 7 d, and the creaming index was 0%, showing good stability. After 6 months of storage, the retention rate of cinnamaldehyde in the microcapsules was about 67.6%, which significantly improved the stability of EOs. Thus, SSOS/MD can efficiently encapsulate EOs with high drug loading, encapsulation efficiency and stability.

Graphical Abstract

Keywords:

• Microcapsules
• starch sodium octenyl succinate
• maltodextrin
• essential oils
• spray drying
• stability

Disclosure statement

The authors report there are no competing interests to declare.

Additional information

Funding

This work was financially supported by the Guangzhou Science and Technology Plan Project (number 201904010112) and the “Yang Fan Plan” team project of Guangdong Province (No. 2017YT05S137).