A hybrid of NiCo-PBNCs nano-composite supported two-dimensional molybdenum disulfide as excellent peroxidase mimics for colorimetric glucose detection

Abstract

The anchoring of two-dimensional nanosheets (2D) with Prussian blue nanocubes has exhibited the advantage of high electron conductivity and better catalytic application. Herein, we reported the successful fabrication of molybdenum disulfide-supported Prussian blue nanocubes (MoS₂@NiCo-PBANCs) and compared the bare MoS₂ and NiCo-PBNCs for effective peroxidase, such as catalytic activity, which can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by the generation of H₂O₂, ensuring the appearance of blue colored solution. The MoS₂@NiCo-PBANCs exhibited an excellent colorimetric sensing performance toward glucose in urine samples. Therefore, the present method demonstrates the high sensitivity, selectivity, simplicity, and fast colorimetric sensing ability for H₂O₂ and glucose detection. The synergistic effect of MoS₂@NiCo-PBNCs reveals lower detection limits of 0.0075 µM and 0.01 µM for H₂O₂ and glucose, respectively. The exclusive structural morphology, excellent stability, large surface area, and high catalytic property have been utilized to achieve the closer interaction of glucose oxidase and TMB with MoS₂@NiCo-PBANCs to oxidize glucose to gluconic acid. Overall, we utilized the MoS₂@NiCo-PBNCs as a novel composite nanomaterial for the application of H₂O₂ and glucose peroxidase-like mimics in the urine sample.

Graphical Abstract

Keywords:

• Peroxidase mimetics
• Prussian blue nanocubes
• MoS₂
• colorimetric sensing
• glucose
• hydrogen peroxide

Acknowledgements

Author acknowledges the support from the Department of Chemistry, Sree Sevugan Annamalai College, Devakottai, and Alagappa University Karaikkudi, Tamil Nadu, India. The authors have confirmed that any identifiable participants in this study have given their consent for publication.

Disclosure statement

The authors declare that they have no competing interests.