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Original Articles

MATHEMATICAL AND EXPERIMENTAL ESSENTIALS OF THE MULSIFICATION PROCESS: OPTIMAL PARAMETERS DETERMINATION

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Pages 59-76 | Published online: 30 Mar 2007
 

ABSTRACT

The evaluation of the procedure for the determination of optimal parameters for the preparation of 0/W emulsions by the mechanical homogenizer has been studied. The method is based on a general functional dependence of the emulsion droplet-size distribution parameters on various factors (homogenization time interval, emulsifi-er concentration, and homogenization intensity) Calculated parameters of the derived mathematical relations were used for characterization of the specific action and limiting capabilities of a particular emulsifier, as well as for the determination of the optimal emulsifica-tion conditions. Changes in emulsifier concentration cause remarkable effects on the emulsion droplet sizes, but only at lower emulsifier concentrations (below the optimal ones). If the homogenization intensity is insufficient, coarse and very unstable emulsions are obtained; if higher than the optimal one, the homogenization effects are not proportional to the energy expended.

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