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Original Articles

THIN LIQUID FILMS FROM WATER-BASED DISPERSIONS OF CELLULOSE ACETHOPHTHALATE IN THE PRESENCE OF PILOCARPINE HYDROCHLORIDE

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Pages 719-731 | Published online: 28 Mar 2007
 

Abstract

The influence of different surfactants on the possibility to obtain fine dispersions with a comparatively high percentage of cellulose acethophthalate (CAP) has been investigated. A method for obtaining concentrated dispersions of CAP including the anti-glaucoma drug pilocarpine hydrochloride has been proposed.

Thin liquid films formed from aqueous CAP dispersions on a glass surface have been investigated as a model of tear films in the eye. The film thickness has been determined by the microinterferometric method. The kinetics of thinning has been studied and discussed.

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