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ABSTRACT
Oil-in-water emulsions of sodium hyaluronate stabilized by nonionic surfactants were analyzed for structural changes during evaporation. The results were compared to the structures found in the appropriate phase diagrams.
The results demonstrated the sodium hyaluronate water content to be extremely high compared to the water content of the water/surfactant lamellar liquid crystal during evaporation and also revealed the sodium hyaluronate to give rise to new association structures at low water contents during evaportation. These structures could not be reproduced by mixing of the components at the corresponding composition.