A Physiological Basis for the Development of Rehabilitative Strategies for Spinally Injured Patients

V. Reggie EdgertonBrain Research Institute, University of California at Los Angeles, Los Angeles, CA;Department of Kinesiology, University of California at Los Angeles, Los Angeles, CA

Roland R. RoyBrain Research Institute, University of California at Los Angeles, Los Angeles, CA

John A. HodgsonBrain Research Institute, University of California at Los Angeles, Los Angeles, CA

Ronald J. ProberDepartment of Kinesiology, University of California at Los Angeles, Los Angeles, CA

Camille P. de GuzmanDepartment of Kinesiology, University of California at Los Angeles, Los Angeles, CA

Ray de LeonDepartment of Kinesiology, University of California at Los Angeles, Los Angeles, CA

ABSTRACT

After a decade of studies using animal models, there is sufficient information to encourage a reassessment of the potential for recovery of motor function following spinal cord injury in humans. This review focuses on the response of the lumbosacral motor system following spinal cord injury and the effects of rehabilitative strategies such as weight support, loading, and administration of specific pharmocological agonists and antagonists on the maintenance and/or recovery of motor function. Based on clinical experience and review of related studies, the authors suggest a list of eight strategies for the improvement of rehabilitative protocols. (J Am Paraplegia Soc 1991; 14: 150–7)

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