Naturally Occurring 1,2-Dithiolanes and 1,2,3-Trithianes. Chemical and Biological Properties

Abstract

This review describes the synthesis as well as the physical and chemical properties of naturally occurring 1,2-dithiolanes and 1,2,3-trithianes. Data on synthetically prepared model compounds are included as background material. The natural occurrence and function, and additional biological activities of these compounds are summarized. Practical applications of chemical and biological properties are presented.

Reagents for the syntheses and chemical transformations as well as physical properties (spectroscopic data, electrochemical data, melting points) are recorded in appropriate tables.

The literature is covered extensively from the first half of 1970 up to the end of 1987. References prior to the former date are included when considered relevant to the current discussion. References from Chemical Abstracts, Vols. 108 and 109 are collected in the addendum. Reports which are not immediately available in English, French or German are cited from Chemical Abstracts.

Key Words:

• 1,2-Dithiolanes
• 1,2,3-trithianes
• synthesis
• natural occurrence
• biological activities
• practical applications