SYNOPTIC ABSTRACT
Consider a nonlinear regression model of the form yk = g(xk;θ)+ek, where θ is an unknown parameter, xk = xk (y1,…,yk-1 is a design variable which depends on previous repsonses for k = 1, 2, …, and e1, e2, … are normal errors. Then the functional form of the maximum likelihood estimator is the same as for deterministic designs, but the sampling distributions may be quite different. Asymptotic expansions for the sampling distributions of normalized estimation error are found, and their use in setting confidence bounds is illustrated. The expansions are unconventional in that a Bayesian approach is used to obtain frequentist properties.