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Abstract
Integral Science provides the empirical rigor needed to shift medicine's worldview. The shift in science will give rise to Integral Medicine, which will emerge from the integration and transformational change of biomedicine, psychosocial approaches, Complementary and Alternative Medicine, and other reform movements. The root metaphor of Integral Medicine is a healthy and sustainable ecosystem. At its heart are mind–body holism and collaborative learning. Healing and the creation of health will emphasize educational, self-care, and community support models. Implications are discussed for practice, research, and education.