A mathematical classification method is presented to show how numerical tests for abnormal anatomical shape change can be used to study geometrical shape changes of the hippocampus in relation to the occurrence of schizophrenia. The method uses the well-known best Bayesian decision rule for two simple hypotheses. Furthermore, the technique is illustrated by applying the hypothesis testing method to some preliminary hippocampal data. The data pool available for the experiment consisted of 10 subjects, five of whom were diagnosed with schizophrenia and five of whom were not schizophrenics. Even though the information used in the experiment is limited and the number of subjects is relatively small, we are confident that the mathematical classification method presented is of significance and can be used successfully, given proper data, as a diagnostic tool.
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.