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Original Articles

Study of Segregation Effects and Fusion Between Lipid Vesicles by Combined Scanning Dilatometric and Calorimetric Measurements

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Pages 1699-1705 | Received 04 Jan 1988, Accepted 17 May 1988, Published online: 25 Sep 2007
 

Abstract

Scanning dilatometric and calorimetric measurements were performed in order to obtain information on correlations between various phenomena involving a lipid vesicle. Scanning dilatometry has been shown to be a fast and reliable tool which gives complementary information to that obtained using differential scanning calorimetry and also, provides a means with which to follow dynamic processes without the introduction of perturbing probes into the lipid matrix. The systems examined were vesicles built up from mixtures of neutral and charged lipids in the presence of mono- and divalent inorganic cations. The studied processes were the gel-liquid crystal transition, lateral phase separation in mixed lipid vesicles and fusion between vesicles.

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