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Original Article

Hypersensitivity to trichophytin in small animals experimentally infected with Trichophyton equinum

Pages 353-361 | Accepted 19 Jun 1989, Published online: 09 Jul 2009
 

Abstract

Typical lesions resulting from experimental Trichophyton equinum infection in laboratory animals persisted for 3–4 weeks. Lesions in rabbits were slightly less severe than those in guinea pigs. In experimentally infected dogs lesions persisted for longer and developed in the form of a deep, crusty dermatophytosis. In skin tests with three trichophytins it was shown that specific hypersensitivity resulting from infection of laboratory animals persists for at least 6 months. Stronger local reactions were produced with homologous trichophytins, especially in the final tests after 6 months.

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