Abstract
Antimycotic susceptibility testing of 17 strains of eumycetes including Madurella mycetomatis, Madurella grisea, Pyrenochaeta romeroi, Exophiala jeanselmei and Leptosphaeria tompkinsii, isolated from cases of black grain mycetoma, was carried out against ketoconazole, itraconazole, miconazole and econazole by broth microdilution and agar dilution methods. Itraconazole and ketoconazole were more active inhibiting 50% of the strains (MIC 50) at 0·5 and 1 µg ml-1 and 90% (MIC 90) at 2·5 and 5 µg ml-1, respectively. The MIC 50s of econazole and miconazole were 2·5 and 5 µg ml-1 and MIC 90s 10 µg ml-1 for both drugs.