Modelling speech motor programming and apraxia of speech in the DIVA/GODIVA neurocomputational framework

ABSTRACT

Background: The Directions Into Velocities of Articulators (DIVA) model and its partner, the Gradient Order DIVA (GODIVA) model, provide neurobiologically grounded, computational accounts of speech motor control and motor sequencing, with applications for the study and treatment of neurological motor speech disorders.

Aims: In this review, we provide an overview of the DIVA and GODIVA models and how they explain the interface between phonological and motor planning systems to build on previous models and provide a mechanistic accounting of apraxia of speech (AOS), a disorder of speech motor programming.

Main Contribution: Combined, the DIVA and GODIVA models account for both the segmental and suprasegmental features that define AOS via damage to (i) a speech sound map, hypothesized to reside in the left ventral premotor cortex, (ii) a phonological content buffer hypothesized to reside in the left posterior inferior frontal sulcus, and/or (iii) the axonal projections between these regions. This account is in line with a large body of behavioural work, and it unifies several prior theoretical accounts of AOS.

Conclusions: The DIVA and GODIVA models provide an integrated framework for the generation and testing of both behavioural and neuroimaging hypotheses about the underlying neural mechanisms responsible for motor programming in typical speakers and in speakers with AOS.

KEYWORDS:

• Apraxia of speech
• speech motor programming
• computational neural modeling
• DIVA
• GODIVA

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Research reported in this publication was supported by the National Institute on Deafness and other Communication Disorders (NIDCD) of the National Institutes of Health under award numbers R01 DC007683, R01 DC002852 (PI: F. Guenther), and T32 DC013017 (PI: C. Moore).