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British Journal of Neurosurgery Volume 32, 2018 - Issue 3
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Review Article

Mechanical thrombectomy – is time still brain? The DAWN of a new era

Naveed KamalDepartment of Neurosurgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA; ORCID Iconhttp://orcid.org/0000-0003-0474-3111
ORCID Icon,
Neil MajmundarDepartment of Neurosurgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA;
,
Nitesh DamodaraDepartment of Neurosurgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA;
,
Mohammad El-GhanemDepartment of Neurosurgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA;
,
Rolla NuomanDepartment of Neurology, Rutgers University, New Jersey Medical School, Newark, NJ, USA;
,
Irwin A. KellerDepartment of Radiology, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA;
,
Steven SchonfeldDepartment of Radiology, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA;
,
Igor RybinnikDepartment of Neurology, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA;
,
Gaurav GuptaDepartment of Neurosurgery, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
,
Sudipta RoychowdryDepartment of Radiology, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA;
&
Fawaz Al-MuftiDepartment of Neurosurgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA; ;Department of Neurology, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA; Correspondence[email protected]
 show all
Pages 245-249 | Received 14 Sep 2017, Accepted 08 Jan 2018, Published online: 08 Feb 2018
 
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Abstract

Purpose: The purpose of this study is to review the history of treatments for acute ischemic stroke, examine developments in endovascular therapy, and discuss the future of the management of acute ischemic stroke.

Methods: A selective review of recent clinical trials for the treatment of acute ischemic stroke was conducted.

Results: We reviewed completed trials of the management of acute ischemic stroke including intravenous thrombolytics, intraarterial thrombolytics, and thrombectomy. We also assessed the future direction of research by reviewing ongoing clinical trials.

Conclusions: The advancement of endovascular treatment for stroke has led to improved morbidity and mortality for patients. Future challenges include delivering these treatments to stroke centers worldwide.

Disclosure statement

No potential conflict of interest was reported by the authors.

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