Gastric Emptying Characteristics of Glucose and Glucose Polymer Solutions

Abstract

In an effort to evaluate various carbohydrate (CHO) molecules for inclusion in an athletic drink, the gastric emptying characteristics of 5, 10, 20, and 40% solutions of glucose and a glucose polymer were compared. The volume of gastric residue remaining 30 minutes after ingestion of 400 ml of each of the solutions was determined in 15 healthy individuals. The volume of gastric residue recovered increased progressively with increasing solute concentration. At the lowest CHO concentration the glucose polymer yielded a significantly smaller gastric residue than glucose. The smaller residue appeared to be attributable both to a greater rate of exit of the polymer from the stomach as well as to a lower rate of gastric secretion induced by the polymer. The calculated delivery of CHO to the intestine increased with solute concentration. At the lowest CHO concentration the more rapid gastric emptying of the polymer allowed significantly greater calculated CHO delivery. We conclude that at low CHO concentrations (≤5 g/100 ml), such as used in drinks designed for athletics participants, the glucose polymer might be an advantageous alternative to glucose as a source of CHO.