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Physiology

Changes in Bone Alkaline Phosphatase and Procollagen Type-1 C-Peptide After Static and Dynamic Exercises

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Pages 49-54 | Published online: 23 Jan 2013
 

We investigated the effects of two types of nonweight-bearing exercise on changes in bone-specific alkaline phosphatase (BAP) and procollagen type 1 C-peptide (P1P). BAP is a specific marker of bone synthesis, whereas P1P reflects synthesis of type 1 collagen in other organs as well as bone. Eight participants performed static and dynamic unilateral knee extensions. BAP and P1P were measured before, and at 1, 2, 24, 48, and 72 hr after exercise. P1P increased at 24 hr after a static knee extension exercise, whereas BAP did not change during the experimental period. We found no changes in these markers after dynamic exercise. These results imply that type 1 collagen synthesis in tendons increases after static exercise.

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Notes on contributors

Keitaro Kubo

Please address correspondence concerning this article to Keitaro Kubo, Department of Life Science (Sports Sciences), University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo 153-8902, Japan

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