Birth Weight is Not Related to Risk of Diabetic Retinopathy in Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

G. Liew Department of Ophthalmology, University of Sydney, Centre for Vision Research, Westmead Hospital, Westmead Millennium Institute, Australia

J. J. Wang Department of Ophthalmology, University of Sydney, Centre for Vision Research, Westmead Hospital, Westmead Millennium Institute, Australia; Centre for Eye Research Australia, University of Melbourne, Victoria, Australia

R. Klein Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, Wisconsin, USA

B. B. Duncan Graduate Studies Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil

H. C. Yeh Departments of Epidemiology and Medicine, Johns Hopkins University, Baltimore, Maryland, USA

F. L. Brancati Departments of Epidemiology and Medicine, Johns Hopkins University, Baltimore, Maryland, USA

P. Mitchell Singapore Eye Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

T. Y. Wong Centre for Eye Research Australia, University of Melbourne, Victoria, Australia; Singapore Eye Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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Abstract

Purpose: Low birth weight has been suggested as a risk factor for diabetes. Whether it is related to diabetic retinopathy is unclear and is examined in this study. Materials and Methods: We examined 609 adults with type 2 diabetes from the population-based Atherosclerosis Risk in Communities Study. Retinal photographs were graded for diabetic retinopathy. Birth weight was assessed by self-report. Results: Retinopathy was present in 116 (19%) participants (113 non-proliferative and 3 proliferative). After adjusting for age, sex, race, education level, body mass index, fasting glucose, duration of diabetes, glycosylated hemoglobin A1c, family history of diabetes, serum total cholesterol, and blood pressure, there was no evidence of either a linear or non-linear relationship between birthweight and diabetic retinopathy. Conclusions: Birth weight was not associated with diabetic retinopathy.

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Birth Weight is Not Related to Risk of Diabetic Retinopathy in Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

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Birth Weight is Not Related to Risk of Diabetic Retinopathy in Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

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