Abstract
Purpose: We aimed to evaluate the dynamic function of iris muscle in asymmetric pseudoexfoliation patients by videonystagmography. Methods: 15 patients with asymmetric pseudoexfoliation and 15 control subjects were included. The function of iris muscle was assessed by the pupillometry test of the videonystagmography by calculating the percent of change in pupillary diameter in unit time during fixation to an accommodative target, light reaction, convergence, and divergence. Results: There were significant differences between groups in the reaction during fixation (p: 0.01), in light reaction (p: 0.014), and in divergence-induced mydriasis (p: 0.003). In all of these, the difference between control eyes and pseudoexfoliative eyes of patients with PXS was significant. Conclusions: Pupillometry seems to be a promising noninvasive method to detect the clinical signs of PXS and may be useful for an accurate diagnosis.