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Cornea and Ocular Surface

A Comparison of the Corneal Thickness Following Descemet’s Stripping Automated Endothelial Keratoplasty and Descemet’s Membrane Endothelial Keratoplasty

, ORCID Icon, , , , , , , , & show all
Pages 712-718 | Received 13 Jan 2023, Accepted 11 Apr 2023, Published online: 20 Apr 2023
 

Abstract

Purpose

To compare the central corneal thickness before and after Descemet’s stripping automated endothelial keratoplasty (DSAEK) and Descemet’s membrane endothelial keratoplasty (DMEK), and to evaluate the recipient corneal thickness following DSAEK.

Methods

The corneal thickness was compared between two groups of eyes following DMEK and DSAEK, performed by a single surgeon between 2015 and 2017. We evaluated the recipient corneal thickness and central corneal thickness pre- and postoperatively at 1, 3, and 6 months using anterior segment optical coherence tomography. Recipient corneal thickness was defined as the corneal thickness without graft thickness.

Results

We included DMEK and DSAEK eyes (n = 26 each), which were similar in terms of their etiologies. Preoperatively, there was no significant difference in the central corneal thickness between the groups (DSAEK, median [interquartile range]: 721 [606.5 to 847.8] µm; and DMEK: 690 [618 to 722.3] µm; p = 0.30). Despite the tendency of the central corneal thickness to be significantly greater (p < .01) at 6 months following DSAEK (619.5 [607.8 to 661.3] µm) compared with that following DMEK (497.5 [475.8 to 525.3] µm), there was no significant difference at 6 months between the recipient corneal thickness following DSAEK (488.5 [443.8 to 515] µm) and central corneal thickness following DMEK (p = 0.54).

Conclusions

DSAEK eyes display a similar tendency of stromal thinning as DMEK eyes.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data that support the findings of this study are available on request from the corresponding author [TH]. The data are not publicly available due to privacy protection in our country.

Additional information

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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