Abstract
The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000 mg kg−1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver > intestine > gill > kidney > muscle. Cu concentration at >125 mg kg−1 reduced growth rate, and was inversely related to growth. The RNA : DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA : DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels.
Acknowledgments
The authors gratefully acknowledge Research Centre, College of Science, King Saud University, Kingdom of Saudi Arabia, for providing funding to carry out the research work.