Extraction, chemical compositions, and cytotoxic activities of essential oils of Thevetia peruviana

Abstract

In this study, The essential oil of flowers, fruits, and leaves of Thevetia peruviana, which were collected in Vietnam, were being reported for the first time. The essential oil of flowers was extracted by different methods: n-hexane extraction, distillation water, and supercritical CO₂ extraction. The compositions of essential oil of different parts of Thevetia peruviana were analyzed by GC-FID and GC/MS systems. Major chemical compositions of essential oil were identified as monoterpenes, sesquiterpenes, terpenoids, and sterol. The activities of total essential oil extracts of the Thevetia peruviana exhibit inhibitory activities against five cancer cell lines.

Keywords:

• Thevetia peruviana
• essential oil
• cancer cell lines
• Vietnam
• anti-cancer activity

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was financially supported by the National Foundation for Science and Technology Development (NAFOSTED) of Vietnam [104.01-2018.348].