Malignant Peripheral Nerve Sheath Tumor of the Oculomotor Nerve

D. Kozic Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

M. Nagulic Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

J. Ostojic Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

M. Samardzic Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

V. Milic-Rasic Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

M. Skender Gazibara Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, Turkey

R. Nuri Sener M.D. Diagnostic Imaging Center, Institute of Oncology, Sremska Kamenica, Serbia and Montenegro; Clinic of Neurosurgery and Clinic of Child Neurology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro; Institute of Pathology, University of Belgrade, Belgrade, Serbia and Montenegro; Department of Radiology, Ege University, Bornova, Izmir, TurkeyCorrespondence[email protected] and [email protected]

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Abstract

We present the short-term follow-up magnetic resonance (MR) studies and ¹H-MR spectroscopy in a child with malignant peripheral nerve sheath tumor of the oculomotor nerve associated with other less aggressive cranial nerve schwannomas. The tumor revealed perineural extension and diffuse nerve involvement besides rapid growth. ¹H-MR spectroscopy was helpful in excluding an intra-axial neoplasm with exophytic growth, mainly due to the absence of creatine and N-acetyl aspartate peaks, and markedly elevated choline peak.

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Malignant Peripheral Nerve Sheath Tumor of the Oculomotor Nerve

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