Acknowledgments
This study was conducted with support from the Centre for Innovative Clinical Medicine, Okayama University Hospital. We thank the following investigators and all other investigators at Okayama University Hospital: Drs. Yosuke Toyota, Satoru Senoo, Takahiro Umeno, Naohiro Oda, Hisao Higo, Chihiro Ando, Atsuko Hirabae, Yoshitaka Iwamoto, and Kammei Rai. We also thank Drs. Mikio Kataoka and Masafumi Fujii as members of the Data and Safety Monitoring Board. We are also thankful to Hiromi Matsushita and Kaori Ohashi for supporting this study.
Disclosure statement
K.H. reports grants and personal fees from AZ, grants and personal fees from Lilly, grants and personal fees from BMS, personal fees from MSD, personal fees from Ono, personal fees from NipponKayaku, personal fees from Taiho, personal fees from BI, and personal fees from Chugai outside the submitted work. K. K. has received honoraria from Eli Lilly Japan, Nihon Kayaku, AstraZeneca, Daiichi-Sankyo Pharmaceutical, Chugai Pharmaceutical, Taiho Pharmaceutical, and Sanofi-Aventis. The remaining authors report no conflicts of interest.