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Review Article: Clinical Oncology

Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms

Gitte Dama Department of Hepatology & Gastroenterology, ENETS Center of Excellence, Aarhus University Hospital, & Department of Clinical Medicine, Aarhus University, Aarhus, DenmarkCorrespondence[email protected]

Henning Grønbæka Department of Hepatology & Gastroenterology, ENETS Center of Excellence, Aarhus University Hospital, & Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

Anna Sundlövb Division of Oncology, Department of Clinical Sciences Lund, Lund University, Sweden

Johan Botlingc Department of Immunology Genetics and Pathology, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden

Anders Sundind Department of Surgical Sciences, Radiology & Molecular Imaging, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden

Rene Horsleben Petersene Department of Cardiothoracic Surgery, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, Denmark;f Department of Clinical Medicine, University of Copenhagen, Denmark

https://orcid.org/0000-0002-3586-1869

Staffan Weling Department of Medical Sciences, Endocrine Oncology Unit, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden

Espen-Thiis Evensenh Department for Organ Transplantation, Oslo University Hospital, ENETS Center of Excellence, Rikshospitalet, Oslo, Norway

Halfdan Sorbyei Department of Oncology, Haukeland University Hospital, and Department of Clinical Science, University of Bergen, Bergen, Norway

Elizaveta Tabaksblatj Department of Oncology, ENETS Center of Excellence, Aarhus University Hospital, Aarhus, Denmark

Anne Kirstine Arveschougk Department of Nuclear Medicine & PET Center, Aarhus University Hospital, ENETS Center of Excellence, Aarhus, Denmark

Jann Mortensenl Department. of Clinical Physiology and Nuclear Medicine, ENETS Center of Excellence & Cluster for Molecular Imaging, Copenhagen University Hospital–Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark

Andreas Kjaerl Department. of Clinical Physiology and Nuclear Medicine, ENETS Center of Excellence & Cluster for Molecular Imaging, Copenhagen University Hospital–Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark

Ulrich Kniggem Departments of Gastrointestinal Surgery and Clinical Endocrinology, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, Denmark

Eva Tiensuu Jansong Department of Medical Sciences, Endocrine Oncology Unit, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden

Seppo W. Langern Department of Oncology, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, and Dept. of Clinical Medicine, University of Copenhagen, Denmark

https://orcid.org/0000-0001-9732-9192

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Abstract

Lung neuroendocrine neoplasms (NEN) are a heterogeneous population of neoplasms with different pathology, clinical behavior, and prognosis compared to the more common lung cancers. The diagnostic work-up and treatment of patients with lung- NEN has undergone major recent advances and new methods are currently being introduced into the clinic. These Nordic guidelines summarize and update the Nordic Neuroendocrine Tumor Group’s current view on how to diagnose and treat lung NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients. This review reflects our view of the current state of the art of diagnosis and treatment of patients with lung-NEN. Small cell lung carcinoma (SCLC) is not included in these guidelines.

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Disclosure statement

Speaker fee: Medtronic, AMBU, Medela, AstraZeneca. Adv. Board: AstraZeneca, Roche, MSD og BMS.

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Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms

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Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms

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