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Letters to the Editor: Medical Oncology

Calcium electroporation as an adjunct therapy for pembrolizumab-resistant bladder cancer: a case report

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Pages 614-620 | Received 13 Mar 2023, Accepted 01 Jun 2023, Published online: 12 Jul 2023
 

Acknowledgements

The authors would like to thank research nurses Tina Sørensen and Cathrine Wolf Lorenzen for their assistance in treatment and follow up. This work did not employ writing assistance.

Ethical approval

The CaEP-B study protocol is approved by the European Union Drug Regulating Authorities (EudraCT no: 2019-004315-31), the Danish Data Protection Agency (REG-114-2019) and Ethics committee for Region Zealand (SJ-811) and registered on Clinicaltrials.gov (NCT04259658). The trial is performed according to Good Clinical Practice (GCP). Clinicaltrials.gov identifier: NCT04259658.

Author contributions

MV was the primary author of the manuscript and performed data curation and data visualisation. MV and JG treated the patient and curated data. LML curated data and performed photo documentation, AJC managed patient treatment and relevant sections in the manuscript. LÖ analysed images and SP and AVL performed histological analyses. All authors read and approved the final manuscript.

Disclosure statement

JG is co-inventor of a patent regarding calcium electroporation: Therapeutic applications of calcium electroporation to effectively induce tumour necrosis. Granted. PCT/DK2012/050496. No other authors declare any conflict of interest.

Data availability statement

De-identified participant data are available from the corresponding author upon reasonable request. Reuse of data requires approval from the pertinent ethics committee.

Consent for publication

In addition to securing written and oral consent for participation in the CaEP-B trial, the authors also obtained signed informed consent specifically for the publication of the case report. This consent encompasses the inclusion of photographs and PET-CT images.

Additional information

Funding

The CaEP-B project was supported by Region Zealand (R17-A36-B30).

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