A case of systemic lupus erythematosus that manifested in the course of schizophrenia

Masanori Funauchi Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Toshiaki Yamagata Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Yuji Nozaki Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Masafumi Sugiyama Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Shin-Ya Ikoma Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Koji Kinoshita Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

Akihisa Kanamaru Department of Hematology, Nephrology and Rheumatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan

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Abstract

A case of schizophrenia is presented in which SLE was diagnosed after 14-year duration. Antibodies to single and double-stranded DNAs, but not to histone, were detected. This case suggests that similar immunological abnormalities as SLE are associated with the pathogenesis of a group of schizophrenia and that class-switch of anti-dsDNA antibodies are important in the pathogenesis of SLE.

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A case of systemic lupus erythematosus that manifested in the course of schizophrenia

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A case of systemic lupus erythematosus that manifested in the course of schizophrenia

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