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Abstract
Objectives: The aim of this study was to determine whether magnetic resonance imaging (MRI)‐related entheseal changes including osteitis and extracapsular oedema could be used to differentiate between metacarpophalangeal (MCP) joint involvement in rheumatoid arthritis (RA) and psoriatic arthritis (PsA).
Methods: Twenty patients (10 each with early RA and PsA) had dynamic contrast‐enhanced MRI (DCE‐MRI) of swollen MCP joints. Synovitis and tenosynovitis was calculated using quantitative analysis including the degree and kinetics of enhancement of gadolinium diethylenetriaminepentaacetic acid (Gd‐DTPA). Periarticular bone erosion and bone oedema were scored using the Outcome Measures in Rheumatology Clinical Trials (OMERACT) proposals. Entheseal‐related features including extracapsular soft tissue enhancement or regions of diffuse bone oedema were also evaluated.
Results: MRI was not able to differentiate at the group level between both cohorts on the basis of entheseal‐related disease but a subgroup of PsA patients had diffuse extracapsular enhancement (30%) or diffuse bone oedema (20%). The RA patient group had a greater degree of MCP synovitis (p<0.0001) and tenosynovitis than PsA patients (p<0.0001). There were no significant differences in either the total number of erosions (p = 0.315) or the presence of periarticular bone oedema (p = 0.105) between the groups.
Conclusion: Although conventional MRI shows evidence of an enthesitis‐associated pathology in the MCP joints in PsA, this is not sufficiently common to be of diagnostic utility.
