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Lack of association between a disease-susceptible single-nucleotide polymorphism, rs2230926 of TNFAIP3, and tumour necrosis factor inhibitor therapeutic failure in Japanese patients with rheumatoid arthritis

H MatsuokaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan;Department of Clinical Research, NHO Osaka Minami Medical Center, Kawachinagano, Japan

D KabataDepartment of Medical Statics, Osaka City University Graduate School of Medicine, Osaka, Japan

A TauraDepartment of Clinical Research, NHO Osaka Minami Medical Center, Kawachinagano, Japan

T MatsuiDepartment of Rheumatology, NHO Sagamihara National Hospital, Sagamihara, Japan

K TakahiDepartment of Orthopedics and Rheumatology, NHO Osaka Toneyama Medical Center, Toyonaka, Japan

F HiranoDepartment of Internal Medicine, NHO Asahikawa Medical Center, Asahikawa, Japan

M KatayamaDepartment of Rheumatology, NHO Nagoya Medical Center, Nagoya, Japan

A OkamotoDepartment of Rheumatology, NHO Himeji Medical Center, Himeji, Japan

Y SuenagaDepartment of Rheumatology, NHO Beppu Medical Center, Beppu, Japan

E SuematsuDepartment of Rheumatology, NHO Kyushu Medical Center, Fukuoka, Japan

S YoshizawaDepartment of Rheumatology, NHO Fukuoka National Hospital, Fukuoka, Japan

K OhmuraDepartment of Rheumatology and Clinical Immunology, Kyoto University, Kyoto, Japan

S ItoDepartment of Rheumatology, Niigata Rheumatic Center, Niigata, Japan

H TakaokaSection of Internal Medicine and Rheumatology, Kumamoto Shinto General Hospital, Kumamoto, Japan

E OguroDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

K KuzuyaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

Y OkitaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

C UdagawaDepartment of Clinical Research, NHO Osaka Minami Medical Center, Kawachinagano, Japan;Department of Molecular Chemistry, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka, Japan

M YoshimuraDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

S TeshigawaraDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

Y HaradaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

K IsodaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

Y YoshidaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

S OhshimaDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan

S TohmaDepartment of Rheumatology, NHO Tokyo National Hospital, Tokyo, Japan

Y SaekiDepartment of Rheumatology and Allergology, NHO Osaka Minami Medical Center, Kawachinagano, Japan;Department of Clinical Research, NHO Osaka Minami Medical Center, Kawachinagano, JapanCorrespondence[email protected]

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Acknowledgement

The present study was supported by a grant from the Japanese National Hospital Organization [H28-NHO Immunological Disorder-02].

Disclosure statement

No potential conflict of interest was reported by the authors.

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Lack of association between a disease-susceptible single-nucleotide polymorphism, rs2230926 of TNFAIP3, and tumour necrosis factor inhibitor therapeutic failure in Japanese patients with rheumatoid arthritis

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Lack of association between a disease-susceptible single-nucleotide polymorphism, rs2230926 of TNFAIP3, and tumour necrosis factor inhibitor therapeutic failure in Japanese patients with rheumatoid arthritis

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