Simple voltammetric sensor detection for puerarin

ABSTRACT

A simple and cost-effective approach for preparation of polyethyleneimine-functionalised graphene (PEI-GR) was proposed for constructing a voltammetric sensor platform. This voltammetric sensor showed strong accumulation ability and excellent voltammetric response for puerarin. The electrochemical behaviour of puerarin was investigated systematically in 0.1 mol L⁻¹ H₂SO₄ (pH 0.8). Under the optimised conditions, a lower detection limit of 8 × 10⁻⁸ mol L⁻¹ (S/N = 3) and a wide linear detection range from 3 × 10⁻⁷ to 1 × 10⁻⁵ mol L⁻¹ were achieved by the linear sweep voltammetry (LSV). Additionally, this effective method was proved to be suitable for the determination of puerarin in Puerarin injection with satisfactory results.

KEYWORDS:

• Puerarin
• polyethyleneimine
• graphene
• voltammetric sensor

Disclosure statement

No potential conflict of interest was reported by the authors.