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Experimental Aging Research
An International Journal Devoted to the Scientific Study of the Aging Process
Volume 5, 1979 - Issue 6
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Methodological comment

Tumor induced brain damage in rats: Implications for behavioral and anatomical studies with aging animals

Donald G. Stein Department of Psychology, Clark University, Worcester, MA, 01610, USA; Department of Neurology, University of Massachusetts Medical School, 01605
&
Elliott J. Mufson Department of Psychology, Clark University, Worcester, Massachusetts, 01610
Pages 537-547 | Received 23 Apr 1979, Accepted 16 Sep 1979, Published online: 27 Sep 2007
 
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Abstract

In rats, spontaneously occurring tumors and infarcts induce damage which destroys or distorts regions of the brainstem and cerebral hemispheres. Despite such destruction, there may be no gross evidence of behavioral or metabolic pathology.

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