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Hemoglobin
international journal for hemoglobin research
Volume 44, 2020 - Issue 2
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Original Articles

Validation of Two Point of Care Devices for Hemoglobin Estimation in Blood Donors

ORCID Icon, ORCID Icon & ORCID Icon
Pages 118-121 | Received 25 Jan 2020, Accepted 14 Mar 2020, Published online: 20 Apr 2020
 

Abstract

Hemoglobin (Hb) estimation is a critical investigation in prospective blood donors. There are numerous techniques for Hb estimation, choosing an appropriate method is essential. Point of care devices (POC) have made quantification of Hb possible even in the field or community settings. Validation against a standard measure is necessary before implementing it for routine practice. With this background, we aimed to validate two new POC devices against a standard hematology analyzer for Hb estimation. An observational study on 100 donor venous blood samples was conducted. Hemoglobin was estimated using a Sysmex Hematology Analyzer (reference method) along with POC devices (CompoLab TM and True Hb Hemometer). Three statistical techniques were applied to validate Hb by the two POC devices. CompoLab TM measures 0.4 units more than the reference method and True Hb measures 0.4 units less than the reference method. Measures of Hb obtained from both the equipment showed moderate agreement with that of reference method (CompoLab TM ICC-0.74 and True Hb ICC-0.72). There were no systematic or proportional differences in the comparison of the two POC devices with the reference method. Within the limitations of this study, both the devices can be used for Hb estimation, as there was a substantial agreement of the measurements with the reference method. Other factors such as cost, turnaround time (TAT), ease of utilization should be considered to decide on the choice of equipment to be used.

Acknowledgments

The authors are grateful to Fresenius Kabi AG, Bad Homburg, Germany and Wrig Nanosystems Pvt. Ltd., Patpargani, New Delhi, India for providing the cuvettes for this study.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.

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