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Hemoglobin
international journal for hemoglobin research
Volume 45, 2021 - Issue 5
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Original Articles

Acute Chest Syndrome in Sickle Cell Disease: Clinical Presentation and Outcomes. The Experience of a Single Thalassemia and Sickle Cell Unit in a University Hospital

, , , , &
Pages 303-308 | Received 15 Jul 2021, Accepted 13 Oct 2021, Published online: 24 Nov 2021
 

Abstract

Acute chest syndrome (ACS) is a common cause of death for sickle cell disease patients. This syndrome is defined as: respiratory symptoms, new X-ray findings developed and/or fever; ACS requires prompt treatment to avoid clinical deterioration and death in adults with sickle cell disease. Sixteen episodes of acute chest syndrome were studied in 16 adults with sickle cell disease. The clinical and radiological findings, treatment, response and outcome of the episode were evaluated respectively. The patient’s past history and comorbidities were taken into account in the outcome and days of hospitalization. Fourteen patients recovered with no sequelae; one patient who required mechanical ventilation also recovered; one patient died due to pulmonary emboli. The mean hospitalization days were 7.43.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.

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