Abstract
Hb Zürich–Albisrieden, [α59(E8)Gly→Arg, HBA1: c.178G>C] is a rare and highly unstable α-globin chain variant. The involved mutation has been reported in both HBA1 and HBA2 genes. A few compound heterozygotes of Hb Zürich–Albisrieden and α0-thalassemia have shown that this variant is associated with severe Hb H disease. We describe here another case of Hb Zürich–Albisrieden who presented with transfusion-dependent anemia beginning shortly after birth.
Disclosure statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.