Polarimetric Parameters to Categorize Normal and Malignant Thyroid Tissue

ABSTRACT

Thyroid tissue samples, pathologically characterized as normal and malignant type, containing both the epithelial and stromal regions are prepared on two different glass slides. Polarized light scattering from these individual slides is used to record the intensity images by Polarimetric Imaging technique. These images are processed further to obtain Mueller intensity images respectively for normal and malignant tissue types. Polar decomposition of these Mueller intensity images results in obtaining Depolarization, Diattenuation, and Retardance images; their potentiality to understand the structural and morphological changes in the samples is reported for comparison.

KEYWORDS:

• Depolarization
• Diattenuation
• Mueller matrix imaging
• polarized light
• Retardance

ACKNOWLEDGEMENTS

The authors would like to acknowledge Dr Padma Sunethri, assistant professor in Pathology Department of Gandhi Medical College, Hyderabad, India for providing the tissue slides and for fruitful discussions.

DISCLOSURE STATEMENT

No potential conflict of interest was reported by the authors.

Additional information

Notes on contributors

Rajkumar Kodela

K. RajKumar received BTech degree in Electronics and Communications and ME degree in Microwave and Radar Engineering from the Osmania University of Hyderabad, India, where he is currently pursuing the PhD degree. Presently, he is working as associate professor in the Department of ECE, in SR Engineering College. His main research interests include biological microwaves and optical imaging techniques applied to soft matter devices. He is a life member of ISTE and IETE.

E-mail: [email protected]

Padmaja Vanagala

V. Padmaja was born in 1968. She received BE degree in Electronics and Communications Engineering and ME degree in Digital Systems Engineering from Osmania University (OU) in 1991 and 1999, respectively. She received PhD degree from Jawaharlal Nehru Technological University (JNTU) in 2009. She is a professor in the Department of ECE in VNRVJIET; her research of interest includes pattern classification, image processing, and embedded systems. She has authored more than 17 research papers in national and international conferences and journals.

E-mail: [email protected]