Synthesis of BSA-Conjugated ZnO Nanoparticle for Pb²⁺ Sensing Applications

Abstract

We report an ultra-low level of Lead ion (Pb²⁺) detection technique using solution-processed Bovine Serum Albumin (BSA) conjugated ZnO nanoparticle (BCZ) networks. Drop of the BCZ solution casting was performed in-between photolithography patterned two Au electrodes for sensor device. BCZ formation was confirmed by UV-Visible spectroscopy (UV-Vis spectroscopy) and Transmission Electron Microscopy (TEM) prior to device fabrication. The working principle of the sensor device depends on the variation of conductance with Pb²⁺ concentration. The limit of detection (LOD) of this fabricated device was determined as 0.1 pM (S/N > 3).

KEYWORDS:

• Bovine serum albumin
• Electron transfer
• Lead ion
• Resistance type
• ZnO nanoparticle

Acknowledgement

Dr. Sasmal would like to acknowledge MEC and MEMS lab, IIT Kharagpur to accomplish this work.

Additional information

Notes on contributors

Milan Sasmal

Milan Sasmal received the bachelor (Hons) degree from Vidyasagar University, Paschim Medinipur, India, and MSc degree from Jadavpur University, Kolkata, India, in 2001 and 2003, respectively both in electronic science. He received MTech degree in materials engineering from the Bengal Engineering and Science University, Shibpur, India, in 2008. He obtained PhD degree from Indian Institute of Technology Kharagpur, Kharagpur, India. He served as assistant professor in Department of Electronics and Telecommunication Engineering, Vidyapratisthan Kamalnayan Bajaj Institute of Engineering and Technology, Baramati, Pune and School of Computing Skills, Bhartiya Skill Development University, Jaipur. Currently, he is assistant professor, in ECE Department, Central University of Rajasthan, Bandersindri, Ajmer. His current research interests include synthesis of various nanostructure and its utilization in sensing applications.

Tarun Kanti Bhattacharyya

Tarun Kanti Bhattacharyya obtained his BSc (Hons) in physics and BTech in radio-physics and electronics in 1984 and 1987, respectively, from the University of Calcutta. He obtained ME and PhD degrees in electronics and telecommunication engineering from Jadavpur University, Kolkata in 1991 and 1996, respectively. He served as a scientist in areas of thin film technology and micro-electronics in reputed laboratories like Indian Association for Cultivation of Science, Central Glass and Ceramic Research Institute, Kolkata and University of Kaiserslautern, Germany. He was a visiting faculty in the University of Washington and the University of Michigan. He is professor Department of Electronics and Electrical Communication Engineering and Advanced Technology Development Centre, Indian Institute of Technology, Khargapur. His current research interests include low power RF IC design, MEMS, and nano electronics. He was a recipient of the UNIDO (Vienna) fellowship in 1992. He has published over 150 papers in reputed journals and international conferences. He is a member of Indo-Japan collaborative committee on Advanced Micro-Nano Manufacturing Science. He is also a member of Indo-US Frontiers of Engineers. He was awarded IBM faculty award for 2012. Email: [email protected]