Montmorillonite K-10 as a Reusable Catalyst for Fischer Type of Glycosylation under Microwave Irradiation

Abstract

Montmorillonite K10 catalyzed Fischer type glycosylation was studied for various monosacharides with different alcohols under microwave irradiation. The method was found to be efficient, economic, simple and time saving and the catalyst montmorillonite K-10 was reused three times without loss of catalytic activity and anomeric selectivity. With glycerol, the method gave products glycosylated at primary alcohols only.

Keywords:

• Montmorillonite K10
• Glycosylation
• glycerol glucoside
• microwave radiation

The authors wish to thank the Director, NEIST, Jorhat for provision of facilities and DKR is thankful to the CSIR, New Delhi, for providing research fellowship.

Notes

^a Isolated yield.

^b The α/β ratio was determined by 300 MHz ¹H NMR spectroscopy.

^a Isolated yield.

^b The α/β ratio was determined by 300 MHz ¹H NMR spectroscopy.

^a Isolated yield.

^b The α/β ratio was determined by 300 MHz ¹H NMR spectroscopy.