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Original Articles

A Novel Approach for the Synthesis of C-Nucleoside Analogs by Constructing Benzoxazine Rings Linked to a Carbohydrate Moiety

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Pages 599-607 | Received 11 Sep 2986, Accepted 17 Jul 1987, Published online: 05 Dec 2006
 

Abstract

Dehydrative cyclization of the condensation product of 2, 3, 4, 5-tetra-O-acetyl-galactaryl chloride with anthranilic acid gave 1, 2, 3, 4-tetra-O-acetyl-1, 4-bis(4H-benzoxazin-4-one-2-yl)-galacto-tetritol. Its reaction with aniline in the presence of phosphorus trichloride afforded 1, 4-bis (3-phenylquinazolin-4-one-2-yl)-1, 2, 3, 4-tetra-O-acetyl-galacto-tetritol.

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