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Original Articles

Synthesis and Properties of Neoglycoconjugates Carrying A Dimerization Motif of Glycophorin A Transmembrane DomainFootnote1

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Pages 633-645 | Accepted 25 Feb 1998, Published online: 22 Aug 2006
 

Abstract

A new class of glycopeptides 8 and 10, were synthesized from 3-carboxypropyl lactoside 4 and tricosapeptide 6 on a solid support. Their amino acid sequences include a dimerization motif of glycophorin A transmembrane domain. The dimerizable properties of the synthesized glycopeptides and non-glycosylated peptides were investigated by Tris-Tricine-SDS-PAGE.

1. Dedicated to the memory of Professor Akira Hasegawa.

2. On leave from Asai Germanium Research Institute Co., Ltd., 1-1-1 Manpukuji, Asaoku, Kawasaki-shi, Kanagawa, 215, Japan.

3. Alternative address: Department of Industrial Chemistry, Tokai University, Kitakaname 1117, Hiratsuka-shi, Kanagawa, 259-12, Japan.

4. Alternative address: Graduate School for Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113, Japan.

Notes

1. Dedicated to the memory of Professor Akira Hasegawa.

2. On leave from Asai Germanium Research Institute Co., Ltd., 1-1-1 Manpukuji, Asaoku, Kawasaki-shi, Kanagawa, 215, Japan.

3. Alternative address: Department of Industrial Chemistry, Tokai University, Kitakaname 1117, Hiratsuka-shi, Kanagawa, 259-12, Japan.

4. Alternative address: Graduate School for Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113, Japan.

Dedicated to the memory of Professor Akira Hasegawa

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