Synthesis of Some Nucleoside Cyclic Ethylene Phosphothionates

S. Parekh Department of Biochemistry & Biophysics, Texas A&M University College Station, Texas, 77843

A. Patel Department of Biochemistry & Biophysics, Texas A&M University College Station, Texas, 77843

C. J. McNeal Department of Biochemistry & Biophysics, Texas A&M University College Station, Texas, 77843

J. Nagyvary Department of Biochemistry & Biophysics, Texas A&M University College Station, Texas, 77843

Abstract

This communication describes the synthesis of 5′-deoxy-5′-chloro-3′-(2-thio-1,3,2-dioxaphosphorinanyl)thymidine, N⁴,2′,3′-triacetyl-5′-(2-thio-1,3,2-dioxaphosphorinanyl)-1-β-D-arabinosyl-cytosine and N⁴-acetyl-5′-(2-thio-1,3,2-dioxaphosphorinanyl)-1-β-D-arabinosylcytosine.

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Synthesis of Some Nucleoside Cyclic Ethylene Phosphothionates

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Synthesis of Some Nucleoside Cyclic Ethylene Phosphothionates

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